Single Dose Curve View
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Graph Information
The single dose view represents the paliperidone plasma concentration following a single administration of up to two INVEGA SUSTENNA® dosage strengths when administered in either the deltoid or gluteal muscle. Uncheck the default example to begin a new comparison.
Consistent with the INVEGA SUSTENNA® Prescribing Information:
- Initiate dosing with 234 mg on treatment day 1 and 156 mg one week later, both administered in the deltoid muscle.
- The INVEGA SUSTENNA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf] recommends a monthly maintenance dose for schizophrenia of 117 mg. Some patients may benefit from lower or higher maintenance doses within the additional available strengths (39 mg, 78 mg, 156 mg, and 234 mg). Administer monthly maintenance doses in either the deltoid or gluteal muscle.
- Following intramuscular injection of single INVEGA SUSTENNA® doses (39 mg - 234 mg) in the deltoid muscle, on average, a 28% higher Cmax was observed compared with injection in the gluteal muscle.
INVEGA SUSTENNA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf]