Single Dose Curve View
Graph Information^ Back to Top
INVEGA TRINZA® Single-Dose Curves
The Single Dose Curve View represents the paliperidone plasma concentration of INVEGA TRINZA® when administered in either the deltoid or gluteal muscle following at least five months of INVEGA SUSTENNA® treatment (two initiation doses and four maintenance doses).
Consistent with the INVEGA TRINZA® Prescribing Information:
- INVEGA TRINZA® is to be used only after INVEGA SUSTENNA® has been established as adequate treatment for at least four months.
- In order to establish a consistent maintenance dose, it is recommended that the last two doses of INVEGA SUSTENNA® be the same dosage strength before starting INVEGA TRINZA®.
- Initiate INVEGA TRINZA® when the next INVEGA SUSTENNA® dose is scheduled with an INVEGA TRINZA® dose based on the previousINVEGA SUSTENNA® dose, using the equivalent 3.5-fold higher dose as shown in table below.
INVEGA TRINZA® Doses for Adult Patients Adequately Treated with INVEGA SUSTENNA®
If the Last Dose of INVEGA SUSTENNA® is:
Initiate INVEGA TRINZA® at the Following Dose:
Conversion from the INVEGA SUSTENNA® 39 mg dose was not studied.
- Administration: For intramuscular injection only by a healthcare professional. Care should be taken to avoid inadvertent injection into a blood vessel.