INVEGA TRINZA® Common Dosing and Administration Topics

Missed Dose

Management of Missed Dose >9 Months Since Last Injection

Consistent with the INVEGA TRINZA® Prescribing Information:

  • If more than 9 months have elapsed since the last injection of INVEGA TRINZA®, re-initiate treatment with INVEGA SUSTENNA® as described in the prescribing information for that product. INVEGA TRINZA® can then be resumed after the patient has been adequately treated with INVEGA SUSTENNA® for at least 4 months.

For illustrative displays of this dosing scenario, please click the links below.

Educational Dose Illustrator for:
INVEGA SUSTENNA® (paliperidone palmitate)
INVEGA TRINZA® (paliperidone palmitate)

The Educational Dose Illustrator can be used to visualize how dosing affects paliperidone plasma concentrations following administration of:

INVEGA SUSTENNA® for:

  • the treatment of schizophrenia in adults
  • the treatment of schizoaffective disorder in adults as monotherapy and as an adjunct to mood stabilizers or antidepressants

INVEGA TRINZA® for:

  • the treatment of schizophrenia in patients after they have been adequately treated with INVEGA SUSTENNA® for at least four months.

This resource simulates the paliperidone plasma concentrations over time resulting from different dosing scenarios that are set forth in the respective Prescribing Information for INVEGA SUSTENNA® and INVEGA TRINZA®. The Educational Dose Illustrator is intended to be used as a resource to foster a better understanding of, and educate healthcare professionals about, the dosing recommendations provided in the respective Prescribing Information for INVEGA SUSTENNA® and INVEGA TRINZA®. It is intended for educational purposes only.

Because the simulated patient paliperidone plasma levels shown in the dosing scenarios are based upon aggregated pharmacokinetic information from clinical studies, the simulations may not be representative of individual patient response.

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This information is intended for healthcare providers in the United States only.

Last updated 8/22/2023

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