Educational Dose Illustrator

INVEGA TRINZA® (paliperidone palmitate) For Schizophrenia

See Important Safety Information throughout this document.

The Educational Dose Illustrator can be used to visualize how dosing affects paliperidone plasma concentrations following administration of:

INVEGA SUSTENNA® for:

INVEGA TRINZA® for:

View this website online by scanning the QR code or visiting the URL below http://www.EducationalDoseIllustrator.com

4th Injection 4 to 9 Months Since 3rd Injection

Graph

Key

  1. Consistent with the Prescribing Information for INVEGA TRINZA® and INVEGA SUSTENNA®:

    • Missing doses of INVEGA TRINZA® should be avoided.
    • In this illustrative example, the fourth INVEGA TRINZA® dose was missed at Week 57. The user can choose whether the dose is missed by either 17 weeks, 24 weeks, 32 weeks, or 36 weeks since the last INVEGA TRINZA® injection by tapping or clicking and dragging the dose box.
    • Therefore, since 4 months up to and including 9 months have elapsed since the last injection of INVEGA TRINZA®, do NOT administer the next dose of INVEGA TRINZA®. Instead, use the re-initiation regimen shown in the table below.

    Re-initiation Regimen After Missing 4 Months to 9 Months of INVEGA TRINZA®

    If the Last Dose of INVEGA TRINZA® was:

    Administer INVEGA SUSTENNA®, two doses one week apart (into deltoid muscle)

    Then administer INVEGA TRINZA® (into deltoid or gluteal muscle)

    Day 1

    Day 8

    1 month after Day 8

    273 mg

    78 mg

    78 mg

    273 mg

    410 mg

    117 mg

    117 mg

    410 mg

    546 mg

    156 mg

    156 mg

    546 mg

    819 mg

    156 mg

    156 mg

    819 mg

    See Instructions for Use for deltoid injection needle selection based on body weight.

    • Note: management of missed doses should only occur on exceptional occasions.

    INVEGA TRINZA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+TRINZA-pi.pdf]

    INVEGA SUSTENNA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf]
Dose Information

Graph Information

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INVEGA TRINZA® Managing a Missed Dose (4 months up to and including 9 months since the last injection)

Consistent with the Prescribing Information for INVEGA TRINZA® and INVEGA SUSTENNA®:

Re-initiation Regimen After Missing 4 Months to 9 Months of INVEGA TRINZA®

If the Last Dose of INVEGA TRINZA® was:

Administer INVEGA SUSTENNA®, two doses one week apart (into deltoid muscle)

Then administer INVEGA TRINZA® (into deltoid or gluteal muscle)

Day 1

Day 8

1 month after Day 8

273 mg

78 mg

78 mg

273 mg

410 mg

117 mg

117 mg

410 mg

546 mg

156 mg

156 mg

546 mg

819 mg

156 mg

156 mg

819 mg

See Instructions for Use for deltoid injection needle selection based on body weight.

INVEGA TRINZA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+TRINZA-pi.pdf]

INVEGA SUSTENNA® Prescribing Information [http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf]

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